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Tag: Hormones

Research Paper 2 min read

REPLENISH Trial: combination capsule of estradiol and progesterone

The REPLENISH study, published in 2017, evaluated a new oral formulation combining estradiol and natural progesterone in a single gelatin capsule for the management of menopausal symptoms. It…

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Research Paper 2 min read

Increased longevity in older users of postmenopausal estrogen therapy: the Leisure World Cohort Study

Long-term research following thousands of women has shown that those who use oestrogen therapy after the menopause tend to live longer than those who do not. The most…

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Research Paper 2 min read

Effects of estrogen on cognition, mood, and degenerative brain diseases

Oestrogen is vital for brain health, supporting blood flow, reducing inflammation and helping nerve cells communicate effectively. As levels fall during the menopausal transition, many women notice changes…

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Research Paper 2 min read

Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol

This study showed that the timing of starting oestrogen therapy matters. Women who began treatment within the first few years after menopause experienced a slowing of artery thickening,…

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Research Paper 2 min read

One-year follow-up of hormone replacement therapy with natural oestradiol and progesterone

This study followed women using a daily combination of body-identical oestradiol and progesterone for one year. The results showed clear improvement in menopausal symptoms, better cholesterol profiles and…

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Research Paper 2 min read

Estrogen and progesterone reduce lipid accumulation in human monocyte-derived macrophages: a sex-specific effect

This study demonstrated that natural female hormones can help protect arteries by reducing the accumulation of fatty deposits that lead to the hardening and narrowing of blood vessels.…

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Research Paper 2 min read

Comparative venous thromboembolic safety of oral and transdermal postmenopausal hormone therapies

A large retrospective study from Switzerland and the United States, involving women aged 40 to 89, found no increased risk of blood clots in those using oral oestrogen…

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Research Paper 2 min read

Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age

This study examined men and women aged 40 to 70 who received a daily dose of DHEA for six months. Restoring DHEA to more youthful levels resulted in…

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Research Paper 2 min read

T4 plus T3 combination therapy for hypothyroidism in patients with persistent symptoms

This study looked at people with hypothyroidism who still felt unwell despite taking standard thyroxine (T4). It found that adding a small amount of T3 to their treatment…

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Research Paper 2 min read

Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men

A study from the University of Western Australia looked at men aged 71 to 89 and found that those with clinically significant depression were much more likely to…

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