Estrogen and progesterone reduce lipid accumulation in human monocyte-derived macrophages: a sex-specific effect

This study demonstrated that natural female hormones can help protect arteries by reducing the accumulation of fatty deposits that lead to the hardening and narrowing of blood vessels. In laboratory testing, oestrogen and progesterone reduced the amount of harmful lipid stored inside immune cells, an early step in artery thickening. These findings suggest that healthy hormone levels may play an essential role in supporting cardiovascular health in women.

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