Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol

This study showed that the timing of starting oestrogen therapy matters. Women who began treatment within the first few years after menopause experienced a slowing of artery thickening, suggesting a protective effect on the cardiovascular system. In women who started treatment much later, this benefit was not as pronounced. The findings support the idea that beginning oestrogen therapy earlier in the menopausal transition may offer better cardiovascular protection than waiting many years after menopause.

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